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Incidence and Diagnoses of HIV Infection -- Puerto Rico, 2006

This report describes the HIV epidemic in Puerto Rico in 2006. The Puerto Rico Department of Health and Centers for Disease Control and Prevention (CDC) analyzed data on diagnoses of HIV infection, including infections that occurred in 2006 and in previous years, and used a stratified extrapolation approach developed by CDC to generate HIV incidence estimates. Results indicate that in 2006, an estimated 1,440 individuals aged 13 years or older were newly infected with HIV.

Two Simultaneous Outbreaks of Multidrug-Resistant Tuberculosis -- Federated States of Micronesia, 2007--2009

This report describes the investigation by the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC), which initially identified five confirmed cases of multidrug-resistant tuberculosis (MDR TB) in two distinct clusters, characterized by two distinct geographic locations, genotypes, and drug-susceptibility patterns in the Federated States of Micronesia. Extensive transmission had occurred among household contacts; 16 (8%) of the 205 contacts identified had confirmed or suspected MDR TB disease, and 124 (60%) had latent TB infection.

Investigation of a Genotype Cluster of Tubercuosis Cases --- Detroit, Michigan, 2004--2007

This report describes the investigation of a genotype cluster of eight tuberculosis cases in US born patients in the Detroit metropolitan area. The investigation was done by the Detroit Department of Health and Wellness Promotion, the Michigan Department of Community Health, and the Centers for Disease Control and Prevention. The first case was reported in a patient with drug-susceptible TB, who subsequently developed multidrug-resistant TB (MDR TB). Seven additional cases were reported in patients with TB genotypes matching that of the index patient.

Sexual and Reproductive Health of Persons Aged 10-24 Years - United States, 2002-2007

This report presents data for 2002-2007 on sexual and reproductive health of persons aged 10-24 years in the United States. Data were compiled from the National Vital Statistics System and multiple surveys and surveillance systems that monitor sexual and reproductive health outcomes. The report addresses three primary topics: (1) current levels of risk behavior and health outcomes; (2) disparities by sex, age, race/ethnicity, and geographic residence; and (3) trends over time.

Updated Guidelines for the Use of Nucleic Acid Amplification Tests in the Diagnosis of Tuberculosis

This report presents the Centers for Disease Control and Prevention's (CDC) updated recommendations on the use of nucleic acid amplification tests (NAA) for TB diagnosis. These revised guidelines were developed on the basis of a report by a panel of clinicians, laboratorians, and TB control officials. The panel was convened by CDC and the Association of Public Health Laboratories (APHL) and in consultation with the Advisory Council for the Elimination of TB (ACET).

Report of Expert Consultations on Rapid Molecular Testing to Detect Drug-Resistant Tuberculosis in the United States

This report presents results from an expert panel convened by CDC to examine the current status of rapid drug-resistance (DR) testing in the United States; to research published evidence and current guidelines; and to provide guidance and make recommendations to CDC for developing a system to provide access to rapid drug-susceptibility testing to all TB control programs in the United States. The panel recommended that CDC establish regional laboratories to provide molecular drug-resistance testing services to state and local TB programs.

HIV Infection Among Young Black Men Who Have Sex With Men --- Jackson, Mississippi, 2006--2008

This report summarizes results of a survey of 29 black 17-25 year-old men who have sex with men (MSM) who were diagnosed with HIV infection during January 2006-April 2008 in the three-county Jackson Mississippi area. The survey was conducted by the Mississippi State Department of Health and the Centers for Disease Control and Prevention (CDC). The study examined risk behavior and HIV testing behavior of the participants.

WHO Policy on TB Infection Control in Health-Care Facilities, Congregate Settings and Households

This report provides World Health Organization (WHO) member states with guidance on preventing TB transmission in healthcare facilities, congregate settings, and households. It focuses on what to do and how to prioritize TB infection control at national levels and includes recommendations for national managerial activities. The report updates or presents new or increased emphasis on the particular administrative and environmental controls to be implemented and on personal protective equipment. It includes a special focus on building design and use of space.

Trends in Tuberculosis Incidence and their Determinants in 134 Countries

This report describes a study that determined whether differences in national trends in tuberculosis (TB) incidence are attributable to the variable success of control programs or to biological, social, and economic factors. Trends in case notifications were used as a measure of trends in incidence in 135 countries from 1997-2006, and regression analysis was used to explore the associations between these trends and 32 measures covering aspects of development, the economy, the population, behavioral and biological risk factors, health services, and TB control.