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Plan to Combat Extensively Drug-Resistant Tuberculosis: Recommendations of the Federal Tuberculosis Task Force

This report was produced by a Federal TB task force that was reconvened by CDC in November 2006. The task force drafted an updated action plan to address the issue of multidrug-resistant TB (MDR TB) and extensively drug-resistant TB (XDR TB). Task force members were charged with articulating the most pressing problems, identifying barriers to improvement, and recommending specific action steps to improve prevention and control of XDR TB in their respective areas.

Mortality Among Patients with Tuberculosis and Associations With HIV Status – United States, 1993-2008

This report provides data on the mortality among patients with TB and associations with HIV infection. To investigate the impact of HIV on risk for death during TB treatment in the United States, data were analyzed for all culture-positive patients with TB from 1993 to 2008. The proportion that died was determined and stratified by HIV test result. Mortality data were restricted to patients reported before 2007.

Syringe Exchange Programs – United States, 2008

This study discusses information on the 184 syringe exchange programs (SEPs) operating in 36 states, the District of Columbia, and Puerto Rico. Of these SEPs, 67% completed a mail/telephone survey conducted by North American Syringe Exchange Network (NASEN) and Beth Israel Medical Center, New York, which covered program operations for 2008. The report summarizes findings from the survey and compares them with results from a previous SEP survey for 1994-2007.

Diabetes Mellitus and HIV

This visual file consists of 37 slides on the medical case management of diabetes mellitus and HIV. It explains the two types of diabetes, the class of HIV drugs that cause kidney problems or worsening of diabetes, the symptoms of peripheral neuropathy, and effective treatment. The online link can be found at http://aidsetc.org/aidsetc?page=etres-display&resource=etres-529.

Updated Guidelines for Using Interferon Gamma Release Assays to Detect Mycobacterium tuberculosis Infection – United States, 2010

This serial presents updated guidelines to US public health officials, healthcare providers, and laboratory workers for use of FDA-approved interferon gamma release assays (IGRAs) to diagnose both active and latent TB infection in adults and children. These guidelines include use of the QuantiFERON-TB Gold In-Tube Test (QFT-GIT) and the T-SPOT.TB Test (T-Spot), two new IGRAs that were not included in the previous guidelines published in 2005. The antigens, methods, and interpretation criteria for these assays differ from those for IGRAs approved previously.