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Updated Guidelines for Using Interferon Gamma Release Assays to Detect Mycobacterium tuberculosis Infection – United States, 2010

This serial presents updated guidelines to US public health officials, healthcare providers, and laboratory workers for use of FDA-approved interferon gamma release assays (IGRAs) to diagnose both active and latent TB infection in adults and children. These guidelines include use of the QuantiFERON-TB Gold In-Tube Test (QFT-GIT) and the T-SPOT.TB Test (T-Spot), two new IGRAs that were not included in the previous guidelines published in 2005. The antigens, methods, and interpretation criteria for these assays differ from those for IGRAs approved previously.

Prevalence and Awareness of HIV Infection Among Men Who Have Sex With Men – 21 Cities, United States, 2008

This report summarizes CDC’s National HIV Behavioral Surveillance System (NHBS) data collected in 2008 from 21 metropolitan statistical areas (MSAs) using an anonymous cross-sectional interview of men at venues where men who have sex with men (MSM) congregate. The data show that of 8,153 MSM interviewed and tested in the 21 MSAs participating in NHBS in 2008, HIV prevalence was 19 percent, with non-Hispanic blacks having the highest prevalence (28 percent), followed by Hispanics (18 percent), non-Hispanic whites (16 percent), and persons who were multiracial or of other race (17 percent).

MMWR: Racial/Ethnic Disparities Among Children with Diagnoses of Perinatal HIV Infection --- 34 States, 2004--2007

This report describes the most recent trends in diagnoses of perinatal HIV infection by race/ethnicity, by summarizing results of analyses of national surveillance data from 34 states from 2004-2007. During 2004-2007, 85 percent of diagnoses of perinatal HIV were in blacks or African Americans (69 percent) or Hispanics or Latinos (16 percent). The average annual rate of diagnoses of perinatal HIV during that time was 12.3 per 100,000 among blacks, 2.1 per 100,000 among Hispanics, and 0.5 per 100,000 among whites.

Decrease in Reported Tuberculosis Cases – United States, 2009

This report discusses the results from the National TB Surveillance System for 2009. A total of 11,540 TB cases were reported in the United States for a TB rate of 3.8 cases per 100,000 population. This was a decrease of 11.4 percent from the rate of 4.2 per 100,000 reported for 2008. This rate was the greatest single-year decrease ever recorded and the lowest recorded rate since national TB surveillance began in 1953.

Monitoring Tuberculosis Programs - National Tuberculosis Indicator Project, United States, 2002-2008

This report summarizes the National Tuberculosis Indicators Project (NTIP) results from 2002-2008, the most recent five-year period for which data are available. NTIP is a secure, web-based monitoring system that uses routinely collected surveillance data on individual TB cases to measure performance of state and local TB programs, help programs prioritize improvement efforts and focus on key TB control activities, and track progress toward national program objectives. Results show that TB program performance was mixed for this period.