The purpose of this program is to fund TA and systems coordination for the 48 counties, Washington, D.C., San Juan, Puerto Rico (PR), and seven states (hereafter referred to as “jurisdictions”) identified in and funded through HRSA-20-078 (the funded entities hereafter referred to as “recipients”). The overarching goal for this initiative is to reduce new HIV infections in the United States. To reduce the new HIV infections in the United States, the EHE initiative focuses on four key strategies: •Diagnose all people with HIV as early as possible; •Treat people with HIV rapidly and effectively to reach sustained viral suppression; •Prevent new HIV transmissions by using proven interventions, including pre-exposure prophylaxis (PrEP) and syringe services programs (SSPs); and •Respond quickly to potential HIV outbreaks to get needed prevention and treatment services to people who need them. The role of HRSA HAB and its recipients under HRSA-25-063 is to focus on Treat and Respond.