Report

This report describes the first US case of transfusion-transmitted HIV infection reported to CDC since 2002. A blood center in Missouri discovered that blood components from a donation in November 2008 tested positive for HIV infection. A lookback investigation determined that this donor had last donated in June 2008, at which time he incorrectly reported no HIV risk factors, and his donation tested negative for the presence of HIV.

This report summarizes data on early syphilis cases reported as of May 31, 2010, in Los Angeles County, California.

This roadmap describes ten priorities, grouped into three core themes, that address the major health and economic impacts of zoonotic TB.

This report discusses community health centers (CHCs) in routine HIV testing consistent with the 2006 recommendations issued by CDC. It explains why it is important for CHCs to routinely offer HIV testing and provides general protocol elements for facility-based HIV testing, such as ensuring confidentiality, implementing alternatives to opt-out HIV testing, testing alternatives and procedures, encouraging patients to return if a confirmatory HIV test is performed, and providing test results to patients.

This report summarizes laboratory and epidemiologic findings associated with reduced susceptibility to azithromycin. It notes that in August-October 2009, five of 55 N. gonorrhoeae isolates obtained from men with symptomatic urethritis tested at San Diego County’s main municipal STD clinic had high azithromycin minimum inhibitory concentrations (MIC)s.

This report discusses the sexually transmitted disease (STD), chlamydia, which is common among sexually active adolescents and young adults. It explains that although chlamydia may be asymptomatic, it can have serious consequences in females, including infertility; hence, the importance of chlamydia prevention. Screening females aged <25 years is ranked by the National Commission on Prevention Priorities as one of the 10 most beneficial and cost-effective prevention services, but it also is one of the most underutilized.

This report provides a summary of responses from a web-based survey of public health laboratories on volume and type of testing for STDs in the United States in 2007. The survey was conducted in 2008. Responses were received from 61.4 percent (94 of 153) participants. In 2007, 3,290,390 chlamydia tests and 3,157,827 gonorrhea tests were performed in the surveyed laboratories; 89.7 percent of chlamydia tests and 84.4 percent of gonorrhea tests were nucleic acid amplification tests. Over 90 percent of responders reported syphilis testing.

This report describes tests of an analysis of data from five laboratories that used reverse sequence screening during 2006-2010 to identify persons with possible untreated syphilis. Three sites served patient populations with low prevalence of syphilis, and two sites served patient population with high prevalence. The results indicated that among sera reactive on initial screening with an automatable treponemal enzyme and chemiluminescence immunoassays (EIA/CIA), 56.7 percent had a nonreactive rapid plasma regain (RPR) test.

The Federal Bureau of Prisons (BOP) Stepwise Approach for Detecting, Evaluating, and Treating Chronic Hepatitis B Virus Infection provides recommendations for the medical management of federal inmates with chronic hepatitis B, or who are otherwise at risk of infection. The treatment of chronic hepatitis B in pregnancy or with hepatocellular carcinoma is beyond the scope of this guideline. For a more in-depth discussion of vaccination strategies and management of blood and body fluid exposures, the reader should refer to the BOP Clinical Practice Guidelines for those topics.