Young people in the United States remain at risk for HIV infection. An estimated 56,300 Americans are infected with HIV each year. Of these, 34%, or approximately 19,000, are adolescents or young adults aged 13–29 years. Young men who have sex with men (YMSM), especially black YMSM, are at highest risk. This information sheet highlights the ongoing risk for HIV infection among YMSM and underscores the need to reach each new generation with effective HIV prevention messages and services. Schools and education agencies are important partners in this effort.