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This report provides guidelines regarding the prevention of needlestick injuries in health care settings. Bloodborne pathogens that may be transmitted during needlestick injuries include HIV, hepatitis B, and hepatitis C. The report identifies activities associated with needlestick injuries and describes Occupational Safety and Health Administration (OSHA) and Food and Drug Administration (FDA) guidelines for the prevention of such injuries in the workplace.

This manual provides information about TB program reviews and planning and technical support. It provides a view of international partnership towards the goal of eliminating TB.

This report discusses the hepatitis C virus (HCV), how it is treated, and how it can be prevented. The report examines the epidemiology of HCV. It discusses the screening tests, history, general treatment, and postexposure prophylaxis for HCV. The report explains the ways that HCV can be transmitted from person to person and how the virus can be spread through bodily fluid. It identifies the most serious high risk behaviors such as injection drug use and certain sexual practices. The report cites the risks associated with health care work.

This manual provides a structured plan for the training, development and evaluation of healthcare workers involved in contact investigation. It focuses on interview techniques and communication skills and provides data collection instruments for the provision of objective feedback to the interviewer.

This study examined the clinic records of TB programs to determine whether these programs used recommended practices to manage HIV-positive persons exposed to TB. The study suggests that TB programs need to review their contact investigation policies, procedures, and outcomes to reduce missed opportunities for preventing active TB among HIV-positive close contacts.

This report describes an outbreak of drug-susceptible TB that occurred in a South Carolina state correctional facility housing HIV-infected inmates and illustrates the need for increased vigilance for TB in settings in which HIV-infected persons congregate.

This report describes findings from two cases in which TB was misdiagnosed due to laboratory cross-contamination and summarizes the results of the ensuing investigation, which demonstrated the value of DNA fingerprinting to identify occurrences of cross-contamination among patient specimens.

This guideline presents updated data about drug interactions between protease inhibitors and non-nucleoside reverse transcriptase inhibitors for treatment of HIV infection together with rifamycins for treatment of TB.

This guideline is intended to provide a framework and understanding of the diagnostic approaches to TB infection/disease and to present a classification scheme that facilitates management of all persons who have had diagnostic tests.

This notice explains that on September 30, 1999, the Food and Drug Administration approved a reformulated amplified Mycobacterium Tuberculosis Direct (MTD) test for detection of Mycobacterium tuberculosis in acid-fast Bacille (AFB) smear-positive and smear-negative respiratory specimens from patients suspected of having TB.