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Updated Guidelines for Using Interferon Gamma Release Assays to Detect Mycobacterium tuberculosis Infection — United States, 2010. Morbidity and Mortality Weekly Report. 59 (RR-5); 1-25, June 25, 2010

This report provides guidance to U.S. public health officials, health-care providers, and laboratory workers for use of FDA-approved IGRAs in the diagnosis of M. tuberculosis infection in adults and children. In brief, TSTs and IGRAs (QFT-G, QFT-GIT, and T-Spot) may be used as aids in diagnosing M. tuberculosis infection. They may be used for surveillance purposes and to identify persons likely to benefit from treatment. Multiple additional recommendations are provided that address quality control, test selection, and medical management after testing.

Country Specific Quick Reference Guides

The Southeastern National Tuberculosis Center in collaboration with the Lung Health Center at the University of Alabama at Birmingham developed TB-specific cultural competency guides. These guides have been adapted into a series of “quick reference guides.” There are quick reference guides for the countries that have accounted for more than 60% of the TB cases among foreign-born persons over the past five years: Mexico, the Philippines, India, Vietnam, China, Guatemala, and Haiti.

Natural Ventilation for Infection Control in Health-Care Settings

Adequate ventilation can reduce the transmission of infection in health-care settings. Natural ventilation can be one of the effective environmental measures to reduce the risk of spread of infections in health care.

This guideline first defines ventilation and then natural ventilation. It explores the design requirements for natural ventilation in the context of infection control, describing the basic principles of design, construction, operation and maintenance for an effective natural ventilation system to control infection in health-care settings.