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Researchers

Behavioral and Biological Surveillance of HIV among Key Populations to Improve HIV-related Services and Utilization in Zambia under the President's Emergency Plan for AIDS Relief (PEPFAR)

The burden of HIV in Zambia is based on data collected from the general population, with prevalence measured at 13.3% among individuals aged 15 – 49 years. Because little is known about the risk of HIV infection among key populations, this FOA aims to provide a mechanism that will tailor a. surveillance system complimentary to population-based surveys for vulnerable groups. Special attention to sensitive sampling of key populations and measurement of risk behaviors illegal under Zambian law is needed in order to provide a better profile and understanding of HIV transmission in Zambia.

Strengthening National Capacity for Integrated HIV/AIDS Health Data Collection, Use, and Dissemination in Support of an Evidence-based Response in South Sudan under the President's Emergency Plan for AIDS Relief (PEPFAR)

The purpose of this FOA is to generate and use quality HIV/AIDS SI including from program data, surveys, and surveillance for an evidence-based HIV Programming in the country. This FOA builds upon 2 of 50 achievements of the current CDC supported project ending March 2017.

Understanding and Addressing the Multi-level Influences on Uptake and Adherence to HIV Prevention Strategies Among Adolescent Girls and Young Women in Sub-Saharan Africa (R21)

This initiative aims to: (1) enhance our understanding of the multi-level factors that influence HIV prevention strategy use among adolescent girls and young women (AGYW) in sub-Saharan Africa and (2) develop and test novel interventions to address these factors and enhance the uptake and adherence to HIV prevention strategies among AGYW in sub-Saharan Africa.

Understanding HIV Persistence in Infants (R01)

The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research in the pathogenesis of perinatal HIV-1 infection by elucidating HIV-1 immune responses in the setting of the infant’s evolving immune system and mechanisms of establishment and maintenance of HIV-1 latent viral reservoirs. The goal of this FOA is to gain knowledge to be used in the future development of strategies to induce HIV-1 remission.

Mechanisms of Immune Activation and Inflammation: HIV Infection, ART, and Drugs of Abuse (R01)

The purpose of this FOA is to promote research to investigate the underlying molecular mechanisms of HIV infection-induced immune activation and inflammation in the presence of antiretroviral therapy (ART) agents and drugs of abuse. The ultimate goal is to obtain information for developing therapeutic interventions for attenuating chronic inflammation-associated comorbidities as well as for restoring or improving ART efficacy in HIV-infected drug-abusing populations.

The Role of Dysbiosis in Cardiovascular, Pulmonary and Hematological Complications During HIV Infection (R01)

The purpose of this Funding Opportunity Announcement (FOA) is to invite basic research project grant applications for HIV Microbiome Centers to perform investigations on the role of HIV-induced dysbiosis and how this imbalance may induce and/or contribute to the occurrence of heart, lung, or blood (HLB) co-morbidities in HIV positive individuals. This FOA will support mechanistic studies that will use in vitro, in vivo, ex vivo, and in silico models applied to HIV research.

Conference for Early Stage HIV/AIDS Vaccine Researchers (R13)

This Funding Opportunity Announcement (FOA) encourages Research Conference Grant (R13) applications to conduct intensive workshop/conference/meeting(s) that address the needs of early stage HIV/AIDS vaccine researchers as they translate preclinical research from nonhuman primates (NHPs) to human clinical trials.

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