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Understanding the Mechanisms of Neuropsychiatric Side Effects and Neurological Toxicities of HIV Medicines (R21 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) invites innovative research grant applications focused on identifying potential mechanisms and risk factors underlying HIV treatment associated neuropsychiatric symptoms and neurological toxicities experienced by some people living with HIV infection. Exploratory and high-risk research projects that may lead to identification of targets for therapeutic interventions or personalized medicine are appropriate for this FOA. Basic and preclinical research in domestic and international settings are of interest.

Computational Models of Immunity (U01 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) solicits applications developing computational models of immunity that advance understanding of the mechanisms required to induce and/or maintain protective immunity to infectious pathogens, other than HIV, and/or vaccines against such pathogens. The main goal of this FOA is to advance development and application of computational models of immunity that are refined through iterative immunological experimentation to validate and improve the utility and robustness of the computational models.

HBV ECHO: Reducing Perinatal Transmission

Video developed through partnership with the Department of Health and Human Resources (HHS) Health Resources and Services Administration's (HRSA) Bureau of Primary Health Care, Project ECHO launched HBV ECHO, a national technical assistance program that helps enhance HRSA-funded health center capacity to reduce perinatal transmission of hepatitis B. Panelists discuss the teleECHO™ curriculum, challenges in addressing perinatal HBV in the primary care setting, and patient case studies.

School Health Policies and Practices (SHHPPS) website

This website contains the data and results from the SHHPPS, a national survey periodically conducted to assess school health policies and practices at the state, district, school, and classroom levels for 2016.

Adipogenesis, Adipocyte Function and Obesity Following HIV Infection, Antiretroviral Therapy, or Pre-Exposure Prophylaxis (R01 Clinical Trial Optional)

The prevalence of obesity is increasing in people with HIV (PWH), contributing to multiple complications associated with this condition. There is mounting evidence that there are unique mechanisms contributing to the development of obesity in PWH versus people without HIV. Furthermore, the biology of the adipocytes might be altered in overweight or obese PWH versus overweight or obese people without HIV.

PrEP for HIV Prevention among Substance Using Populations (R01 Clinical Trial Optional)

NIDA is interested in research that addressing research gaps related to PrEP and its use among substance users, with the goals of improving PrEP management and implementation. Current US Public Health Service PrEP guidelines recommend PrEP for people who inject drugs (PWID) and mention alcohol and illicit drug use as potential concerns for clinical management. Only one clinical trial has evaluated PrEP among PWID and systematic data regarding the broader use of PrEP among substance users are limited.

Mathilde Krim Fellowships in Biomedical Research

The goal of amfAR’s Mathilde Krim Fellowships in Biomedical Research is to: Facilitate the exceptional postdoctoral researcher’s transition to an independent career in HIV/AIDS research within an academic institution or nonprofit organization; support two years of postdoctoral biomedical research (phase I); provide the possibility of one additional year of research funding during the first year of an independent research position (phase II). 

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