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Treatment Guidelines Materials

Evidence-based Tuberculosis Diagnosis

This website is a comprehensive source of evidence syntheses, policies, guidelines, and research agendas on TB diagnosis. The website offers detailed guidance on how to conduct and report diagnostic research on TB, guidance on how to perform systematic reviews of diagnostics, tools on guideline development, including GRADE, and documents on improvement of laboratory quality and practice. All information is provided as open access, with no registration or fee requirements.

Treatment of Tuberculosis (TB) - Online Refresher Course

The TB course is intended as a refresher course for physicians (both public and private) that may be involved in the management and care of patients with TB. The course is developed as a preparation course to the MDR-TB course of WMA and both courses together offer a complete training module on TB. The refresher course will provide basic clinical care information for TB including the latest diagnostics, treatment and information about multidrug-resistant TB.

Updated Guidelines for Using Interferon Gamma Release Assays to Detect Mycobacterium tuberculosis Infection — United States, 2010. Morbidity and Mortality Weekly Report. 59 (RR-5); 1-25, June 25, 2010

This report provides guidance to U.S. public health officials, health-care providers, and laboratory workers for use of FDA-approved IGRAs in the diagnosis of M. tuberculosis infection in adults and children. In brief, TSTs and IGRAs (QFT-G, QFT-GIT, and T-Spot) may be used as aids in diagnosing M. tuberculosis infection. They may be used for surveillance purposes and to identify persons likely to benefit from treatment. Multiple additional recommendations are provided that address quality control, test selection, and medical management after testing.