Syphilis

This guide was created to help educate physicians and healthcare providers on the diagnosis, treatment, and prevention of syphilis.

This video examines the reported surge in congenital syphilis, and presents specific actions health providers can take to help protect their pregnant patients and their babies.

This video discusses how congenital syphilis rates continue to rise, but many cases can be prevented with education and early screening.

This journal article shows that Syphilis incidence has increased significantly in the US, raising concerns about onward transmission. Using near-real-time data, this study examined monthly trends in syphilis incidence among US adults from January 2017 to October 2024, focusing on overall patterns and stratifying by demographic and clinical characteristics.

This module is designed to introduce student providers to the most common sexually transmitted infections (STI) in the region and indications for screening/testing. Careful consideration of patient history, current symptoms, and local STI rates will allow the student to select efficient laboratory testing to reduce time to treatment and unnecessary testing. This module will provide a basic understanding of the timing and interpretation of serological, molecular, and microscopic screening for patients who have contracted, currently or in the past, an STI.

This module is the third installment in the Sexually Transmitted Infections (STI) series and will focus on treatment of the most common treatable STIs in the United States, including syphilis, gonorrhea, chlamydia, and trichomoniasis. Students will virtually interact with simulated patients to learn how to interpret STI testing results, select the appropriate guideline-directed treatment option, and practice counseling patients regarding STI treatment. This module will help prepare students to treat patients in the RESPECT clinic and in clinical practice.

This fact sheet highlights the rising rates of syphilis and congenital syphilis, emphasizing the importance of prevention, timely testing, and antibiotic treatment. It underscores that nearly 90% of congenital syphilis cases can be prevented through early detection and treatment during pregnancy.

This fact sheet highlights the rising rates of syphilis and congenital syphilis, emphasizing the importance of prevention, timely testing, and antibiotic treatment. It underscores that nearly 90% of congenital syphilis cases can be prevented through early detection and treatment during pregnancy.

This journal discusses a case of tertiary syphilis leading to ocular syphilis and complications such as retinal detachment. It highlights the diagnostic challenges, treatment approaches, and clinical implications of late-stage syphilis affecting the eyes.

This video features Christopher Golden, a neonatologist at Johns Hopkins Children’s Center, discussing the alarming rise in congenital syphilis and its implications for pediatric care.