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Diagnostic Tests

Feasibility of Novel Diagnostics for TB in Endemic Countries (FEND for TB) (U01 Clinical Trial Not Allowed)

The objective of this Funding Opportunity Announcement (FOA) is to support the evaluation of early stage diagnostics and novel diagnostic strategies for Tuberculosis (TB) in the context of existing clinical diagnostic algorithms in TB endemic countries. Evaluation studies should focus on: 1) proof-of principle studies of novel diagnostic tests and strategies and 2) provide feedback to diagnostic developers on the performance of the technology and most effective strategy for use of a diagnostic technology in an endemic setting. 
 

Advancing Biomarker Discovery and Novel Point-of-Care Diagnostics for Active TB Disease Detection in HIV-1 Infected and Exposed Children (R01 Clinical Trial Optional)

The objective of this FOA is to advance non-sputum-based tuberculosis (TB) diagnostics for use in HIV-1 infected and HIV-1 exposed uninfected children (HEU) for improved, simplified, rapid and decentralized diagnosis of TB disease. This opportunity will support discovery and validation of novel biomarkers useful for TB diagnosis or the development/optimization and early validation of novel TB diagnostic technologies. 

Comprehensive Cervical Cancer Control: A Guide to Essential Practice

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This guide includes WHO recommendations on screening and treatment of pre-cancer lesions and on HPV vaccination made through April 2014, taking account of relevant evidence-based findings published up to December 2013; emerging practices that are still being evaluated are also noted in this publication. This guide, which replaces the 2006 edition, has two new chapters, one newly organized chapter, and two substantially revised chapters. The new chapters include: Essentials for cervical a=cancer prevention and control programmes; and HPV vaccination.

Hepatitis C: Información sobre pruebas y diagnóstico

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This information sheet discusses testing and diagnosing hepatitis C virus infection (HCV). It describes hepatitis C, a serious liver disease, and notes that some people do not know they have disease because they experience no symptoms. The information sheet explains hepatitis C transmission, who should be tested, why it is important to be tested, the blood test doctors use to diagnose HCV and the meaning of the test results, and where to find additional information.

Hepatitis C: Information on Testing & Diagnosis

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This information sheet discusses testing and diagnosing hepatitis C virus infection (HBV). It describes hepatitis C, a serious liver disease, and notes that some people do not know they have disease because they experience no symptoms. The information sheet explains hepatitis C transmission, who should be tested, why it is important to be tested, the blood test doctors use to diagnose HCV and the meaning of the test results, and where to find additional information.

Hepatitis C: Liver Biopsy

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This information sheet discusses the liver biopsy. It explains a liver biopsy; the risks involved; how a liver biopsy can help, particularly for people with Hepatitis C; how it is done; and what happens after the liver biopsy is done. It also discusses when one should not have a liver biopsy. The information sheet specially emphasizes that a person who takes medicine for hepatitis C might need to have more than one liver biopsy.

Frequently Asked Questions About Hepatitis C: Sexual Transmission of HCV

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This information sheet is an FAQ that features answers to posed questions about hepatitis C virus (HCV) and and liver biopsy. Questions include: What is a liver biopsy?; What happens during a liver biopsy?; What happens after a liver biopsy?; What are the risks from a liver biopsy? and What about a Fibroscan?

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