MMWR: Update: Prevention of Hepatitis A After Exposure to Hepatitis A Virus and in International Travelers. Updated Recommendations of the Advisory Committee on Immunization Practices (ACIP)

This report presents updated recommendations made by the Advisory Committee on Immunization Practices (ACIP) for prevention of hepatitis after exposure to hepatitis A virus (HAV) and for departing international travelers. The recommendations incorporate existing ACIP recommendations for hepatitis A prevention. The recommendations were updated based on evidence of a randomized, double-blind noninferiority clinical trial, comparing the efficacy of hepatitis A vaccine and immune globulin (IG) after exposure to HAV, and the expert opinions of workgroup members, other scientists, and feedback from ACIP partner organizations.