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Tuberculosis (TB), a contagious bacterial infection primarily affecting the lungs, remains a health risk in the U.S. Though cases declined for decades, recent increases — including ~10,347 cases in early data from 2024 — suggest testing and treatment of latent TB is needed more than ever.  Testing is crucial both for diagnosing latent TB (where bacteria are present but symptoms are absent) and active TB disease (which is contagious and manifests symptoms).

Syphilis remains a persistent sexually transmitted infection that requires rigorous diagnosis and management to prevent transmission, progression, and severe complications. This guideline distilled by Praxis Medical Insights outlines the current consensus from the Centers for Disease Control and Prevention (CDC) and related professional bodies on optimal screening methods, diagnostic interpretations, and treatment regimens.

Human papillomavirus (HPV) infects nearly 80% of people at some point during their lives, and while the immune system clears most infections, persistent HPV can lead to genital warts and several cancers (cervical, anal, vulvar, vaginal, penile, and oropharyngeal). HPV vaccination offers strong protection—preventing more than 90% of HPV-related cancers—and is most effective when administered before HPV exposure.

The webpage highlights the disproportionate rates of Hepatitis C virus among American Indian/ Alaska Native communities. This webpage highlights the Cherokee National Health Services acute Hepatitis C virus (HCV) elimination program, which provides community based testing at food distribution centers, universal screening, and rapid point of care diagnostics. Programs such as HCV and Linkage to Program (HELP) use telehealth to connect patients with providers. Project ECHO builds clinical capacity for local practitioners.

This tool is intended to facilitate the calculation of the number of infections and other health outcomes averted, and the associated savings in direct medical costs and productivity costs, by STI prevention program activities as described in this User Guide and supporting scientific manuscript and appendix. 

This report evaluates the current needs, protocols, and promising practices for latent tuberculosis infection (LTBI) and tuberculosis (TB) screening, testing, and treatment among community health centers serving Asian American/Asian (A/AA) and Native Hawaiian/Pacific Islander (NH/PI) populations.

This report summarizes the TB Elimination Alliance's (TEA) activities and outcomes from 2019 to 2024.

This webpage explains Assembly Bill 2132, which mandates tuberculosis (TB) risk assessment and testing for adult primary care patients in California.

This video discusses how congenital syphilis rates continue to rise, but many cases can be prevented with education and early screening.

This information sheet outlines how the Pennsylvania Department of Health improved STI treatment reporting by partnering with REDCap to streamline its PA-NEDSS system. It highlights key steps and considerations for jurisdictions aiming to enhance data quality or implement new reporting programs.