Persons with HIV (PWH) living in rural communities may have limited access to HIV care providers and may need to travel long distances to visit an experienced HIV care provider. Additionally, Black and Hispanic/Latino PWH may experience structural barriers such as racism and lack of access to language translation services that may make it challenging to adhere to routine HIV care and treatment services. These barriers can be exacerbated in rural communities.

The purpose of this notice of funding opportunity (NOFO) is to develop technologies to improve the delivery of pharmacological, gene editing, or other cargoes for HIV and substance use disorder (SUD) mechanistic or therapeutic research.

The purpose of this NOFO is to support the Ending the HIV Epidemic in the U.S. (EHE) initiative by scaling up HIV prevention services in sexual health clinics. Recipients funded under this NOFO will: 1) strengthen clinic infrastructure and improve service delivery to address the syndemic of HIV & STIs, 2) foster strategic partnerships in support of EHE, and 3) conduct specialized evaluation studies on EHE-related clinic activities.