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HIV and Injection Drug Use Syringe Services Programs for HIV Prevention

This Vital Signs highlights the importance of expanding access to SSPs, which provide sterile needles and syringes and ideally offer many other comprehensive services to help improve the health of PWID and their communities, such as treatment for substance use disorder, HIV, and hepatitis testing and linkage to treatment, and safe disposal of used syringes.

Recommendations for the Use of Antiretroviral Drugs During Pregnancy and Interventions to Reduce Perinatal HIV Transmission in the United States

This guideline offers updated, evidence-based recommendations—from preconception through postpartum—on universal prenatal HIV testing, preferred antiretroviral regimens (e.g., bictegravir/TAF/FTC), maternal viral monitoring, obstetric management, and neonatal prophylaxis to further reduce perinatal HIV transmission toward elimination goals (defined as <1% transmission rate and <1 infection per 100,000 live births).

Alternative Funding Programs Issue Brief (AFPs). AIDS Drug Assistance Program Benefits Management.

This information sheet offers an in-depth analysis of current AFP models—including funding mechanisms, stakeholder roles, and implementation strategies—to support sustainability of HIV-related services beyond traditional grant funding. It outlines key considerations and best practices to help health departments and community partners explore and launch innovative financing options for long-term epidemic response planning.

AIDS Drug Assistance Program Benefits Management Toolkit

This toolkit supports Ryan White HIV/AIDS Program (RWHAP) Part B AIDS Drug Assistance Programs (ADAPs)—which provide access to HIV-related medications for low-income individuals—in navigating the planning, selection, and implementation of benefits management contracts. It offers key definitions, planning tools, real-world examples, and checklists to help ADAP administrators—new or experienced—align contractor selection with their program’s unique infrastructure and needs.

HRSA/CDC Integrated HIV Prevention & Care Plan Guidance Recipient Training

In this webinar, CDC and HRSA speakers review the calendar year 2027–2031 Integrated HIV Prevention & Care Plan Guidance—highlighting key updates, submission requirements, and real-world recipient examples. The training equips CDC- and HRSA-funded jurisdictions with technical support, planning tools, and strategies to develop coordinated HIV prevention and care efforts by the June 30, 2026 deadline.

High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use.