HPV Vaccine: What age is too late?

Human papillomavirus (HPV) infects nearly 80% of people at some point during their lives, and while the immune system clears most infections, persistent HPV can lead to genital warts and several cancers (cervical, anal, vulvar, vaginal, penile, and oropharyngeal). HPV vaccination offers strong protection—preventing more than 90% of HPV-related cancers—and is most effective when administered before HPV exposure. The Centers for Disease Control and Prevention (CDC) recommends beginning vaccination at ages 9 to 14 with two doses, or three doses for those aged 15-26 (or immunocompromised individuals). For adults aged 27-45 who haven’t been vaccinated, discussions with a healthcare provider are advised to assess benefits; after age 45, vaccination is not recommended. Completing the full dosing schedule appropriate for one’s age is crucial for optimal protection. The article emphasizes that while earlier vaccination is best, it’s not too late for many adults in eligible age brackets to gain meaningful protection.