The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major histocompatibility complex (MHC) class I types, because MHC class I genotypes have large effects on macaque immune responses to Simian Immunodeficiency Virus (SIV) that can induce AIDS in nonhuman primates (NHPs) and on human immune responses to HIV.
Limited Competition: Specific Pathogen Free Macaque Colonies (U42 Clinical Trial Not Allowed)
Funding Organization:
The US Department of Health and Human Services National Institutes of Health
Funding Category:
HIV/AIDS
Other Health-Related
Support Types:
Cooperative Agreements
Locations:
National
Eligible Organizations:
Fund ID:
PAR-24-078
Application Due Date:
Subjects:
Clinical Research
Data Analysis
Health Care Planning
Health Care Programs/Services
HIV
Research
Audiences:
At Risk Persons
Persons with HIV/AIDS
Researchers
Last Updated: