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Evaluations to Improve Prevention Interventions Under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Department of Health and Human Services

PEPFAR is committed to reducing new HIV infections worldwide by implementing evidence-based interventions that address risk at the individual, relationship, and community level. Adolescent girls and young women (AGYW) ages 15 to 24 years in sub-Saharan Africa are unique with respect to both their high burden of HIV disease and their extensive array of potential risk factors at the biological, behavioral, interpersonal, social, and structural levels.

HIV Program Evaluation Implementation Support for Activities Implemented under the President's Emergency Plan for AIDS Relief (PEPFAR)

This funding opportunity announcement (FOA) will directly support public and nonprofit private institutions and agencies in PEPFAR-supported countries for the conduct of evaluations of programs currently being implemented by CDC-funded partners. These activities are essential for establishing and strengthening innovative, emerging, and best practices in clinical and community HIV/AIDS and TB prevention, care, and treatment services provided in PEPFAR-supported countries, and may include economic, process, and outcome evaluations.

Scale-up of Community HIV Testing and Counseling (CHTC), Linkage to Care (LTC), Comprehensive Support for Key Population (KP) Activities and Combination Prevention Project Implementation Activities in Botswana u

Support implementation of public health programs in the areas of HIV prevention, care and treatment to advance implementation science activities in Botswana. The purpose of this program is to increase access to and utilization of high quality, integrated, confidential, voluntary client- (VCT) and provider-initiated (PITC) HIV testing and counseling (HTC). Project activities will including HIV testing, counseling, linkage to care, and coordination of various project activities to optimize the full cascade of HIV/AIDS-related services in key geographic areas and within key populations.

Program for Testing, Care, Treatment, and Prevention of HIV/AIDS (PROTECT) among Key Populations: Men who have Sex with Men and Commercial Sex Workers in the Republic of Cote d'Ivoire under PEPFAR

US CDC will through this FOA, award to a consortium with the purpose of establishing a self-sustaining comprehensive clinical and community Program for Testing, Care, Treatment, and Prevention for HIV/AIDS (PROTECT) for men who have sex with men (MSM), Female sex workers (FSW), and evidence based selected priority populations in Cote d’Ivoire to increase the adoption of high impact HIV services and protective behaviors among at-risk populations in targeted locations.PROTECT aims to: i) accelerate the ability of partner governments, key population (KP) civil society organizations and private

Peer-to-Peer Support for ART Adherence, Retention in Care, Linkage to Comprehensive HIV Services and Linkage of PLHIV Families and Contacts to HIV Testing Services in the Federal Democratic Republic of Ethiopia under PEPFAR

This FOA will support national facility based case management activities implemented through associations of persons living with HIV (PLHIV). Activities include peer support for HIV treatment adherence, preventing and minimizing loss-to-follow-up and improving retention in care, and facilitating linkage of all HIV patients and others affected by HIV to comprehensive HIV services.

Accelerating Epidemic Control in Mubende Region in the Republic of Uganda under the President's Emergency Plan for AIDS Relief (PEPFAR)

The primary objective of this FOA is to accelerate HIV/AIDS epidemic control and attain the UNAIDS 90-90-90 goals using the Test and Start approach combines with efficient models of service delivery. In the scale-up districts, the awardee will provide a package of services that will result achievement of the 90-90-90. The awardee will create site and community level demand for HIV prevention, targeted testing, counseling, and care services. For Sustained districts, the awardee will provide passive enrollment via HIV testing and counseling (HTC) on request or as indicated by clinical symptom

Accelerating Epidemic Control in Masaka Region in the Republic of Uganda under the President's Emergency Plan for AIDS Relief (PEPFAR)

The primary objective of this FOA is to accelerate HIV/AIDS epidemic control and attain the UNAIDS 90-90-90 goals using the Test and Start approach combines with efficient models of service delivery. In the scale-up districts, the awardee will provide a package of services that will result achievement of the 90-90-90. The awardee will create site and community level demand for HIV prevention, targeted testing, counseling, and care services. For Sustained districts, the awardee will provide passive enrollment via HIV testing and counseling (HTC) on request or as indicated by clinical symptom

Accelerating Epidemic Control in Soroti Region in the Republic of Uganda under the President's Emergency Plan for AIDS Relief (PEPFAR)

The primary objective of this FOA is to accelerate HIV/AIDS epidemic control and attain the UNAIDS 90-90-90 goals using the Test and Start approach combines with efficient models of service delivery. In the scale-up districts, the awardee will provide a package of services that will result achievement of the 90-90-90. The awardee will create site and community level demand for HIV prevention, targeted testing, counseling, and care services. For Sustained districts, the awardee will provide passive enrollment via HIV testing and counseling (HTC) on request or as indicated by clinical symptom

Strengthening the Capacity of Faith Based Organizations (FBOs) in Accelerating a Comprehensive and Integrated Approach to Providing HIV/AIDS/TB/STI Care, Treatment and Prevention Services in Zambia under the President's Emergency Plan for AIDS Relief

This FOA will support (strengthen) Faith Based Organizations in Zambia to provide support for HIV/AIDS service delivery in facilities that serve the religious communities (in facilities and communities they serve). Overall, this FOA will aim to support the Government of Zambia’s response towards sustainable HIV epidemic control by: a) reducing new HIV infections, b) reducing morbidity and mortality among adults and children living with HIV; and c) strengthening health support systems.

Behavioral and Biological Surveillance of HIV among Key Populations to Improve HIV-related Services and Utilization in Zambia under the President's Emergency Plan for AIDS Relief (PEPFAR)

The burden of HIV in Zambia is based on data collected from the general population, with prevalence measured at 13.3% among individuals aged 15 – 49 years. Because little is known about the risk of HIV infection among key populations, this FOA aims to provide a mechanism that will tailor a. surveillance system complimentary to population-based surveys for vulnerable groups. Special attention to sensitive sampling of key populations and measurement of risk behaviors illegal under Zambian law is needed in order to provide a better profile and understanding of HIV transmission in Zambia.

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