The One & Only Campaign raises awareness among patients and healthcare providers about safe injection practices. The campaign aims to eradicate outbreaks resulting from unsafe injection practices. The goal of the campaign is to ensure patients are protected each and every time they receive a medical injection. This will be attained by empowering patients and re-educating healthcare providers regarding safe injection practices. Targeted education and awareness campaigns focus on influencing the culture of patient safety.

Inspired by the statistic that one in 17 Wyoming youth between 15 and 25 years old has an STD, the Wyoming Department of Health is reorganizing its KnoWyo program to target a younger audience between the ages of 13 and 25. The federally funded program allows individuals to print a voucher for free STD and HIV tests at local clinics. The campaign emphasizes using the hashtag #make1countare on its Facebook and Twitter pages. The hashtag slogan is meant to encourage youth to collect a urine sample for testing from one of the estimated 2,500 times in a year that they will go to the bathroom.

San Francisco Hep B Free is a citywide campaign that seeks to turn San Francisco into the first hepatitis B free city in the nation. This campaign provides free and low-cost hepatitis B testing and vaccinations to Asian and Pacific Islander (API) adults at locations throughout San Francisco.