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Medical Treatments and Therapies

Ryan White HIV/AIDS Program Part C Capacity Development Program

This notice announces the opportunity to apply for funding under Ryan White HIV/AIDS Program (RWHAP) Part C Capacity Development Program. The purpose of this program is to strengthen organizational capacity to respond to the changing health care landscape and increase access to high quality HIV primary health care services for low income, uninsured, and underserved people living with HIV (PLWH).

Scaling High Quality Laboratory Services for HIV Diagnosis, Care, Treatment and Monitoring in Mozambique under the President's Emergency Plan for AIDS Relief (PEPFAR)

Laboratory services, and their networks, are fundamental components of effective, well-functioning health systems and are essential for patient management, disease detection and control, and surveillance. This NOFO will support Mozambique’s Ministry of Health (MOH) to strengthen the integrated national laboratory network in order to ensure the provision of quality services for clinical diagnosis, screening, and surveillance in support of HIV care and treatment and the achievement of an AIDS free generation.

Strengthen Capacity of South African Government's Department of Health and Implementing Partners to Deliver Quality Differentiated, Advanced Clinical Care for Unstable HIV and TB/HIV Patients in the Republic of South Africa under PEPFAR

In South Africa, it is estimated that 20% of patients newly initiating anti-retroviral therapy (ART) present late and 10-15% of patients on first line ART are failing treatment, leading to poor retention, especially in the first 12 months of treatment. This NOFO seeks to improve treatment retention and viral load suppression of HIV and TB/HIV co-infected patients through the use of innovative capacity building approaches for health service providers to better manage complicated and unstable HIV and TB/HIV co-infected patients.

Strengthening the Health System Capacity to Implement HIV Prevention, Care, and Treatment Services in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR)

This project will have an important role in the attainment of PEPFAR and UNAIDS 95-95-95 goals in the Republic of South Africa. In alignment with World Health Organization (WHO) health system building blocks, activities will reflect the South African National Department of Health’s priorities in human resources for health (HRH), service delivery, information systems, and leadership and governance for sustainable results.

Initiative for TB/HIV Program Collaboration and Service Integration in the Central America Region under the President's Emergency Plan for AIDS Relief (PEPFAR)

Globally, Tuberculosis (TB) causes one third of all HIV-related deaths. The TB/HIV collaborative activities that decrease TB among PLHIV when combined with ART include TB screening, TB preventive therapy, and TB infection control. In the Central America Region, there is no integration of TB and HIV programs: gaps remain in TB/HIV collaborative activities, registries are incomplete and inaccurate, and many health care workers (HCW) have limited experience in TB/HIV care and treatment.

Long-acting Drug Delivery Systems for ART Optimization in HIV-1 Infected Children (R61/R33 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to accelerate development of safe and effective long-acting drug delivery systems (LA-DDS) for improved, simplified treatment of HIV-1 in children. This FOA invites applicants engaged in the development of existing LA-DDS platforms at early product development stages to perform specific preclinical activities that enable product optimization and accelerated translation to HIV-1 infected children. Collaborative research partnerships with industry are required.

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