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Drug Resistance

Tuberculosis in Women

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This information sheet discusses the burden and challenges of TB in women. It states that TB is the second leading cause of death from a single infectious agent worldwide.

TB/HIV: HIV-Associated Tuberculosis

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This information sheet discusses the challenges and key issues of the co-infection of TB and HIV. It states that TB is the leading cause of the death among people with HIV.

A New Tool to Diagnose Tuberculosis: The Xpert MTB/RIF Assay

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This information sheet discusses the Xpert MTB/RIF Assay for diagnosing TB. It explains that the new test is a nucleic acid amplification test that diagnoses TB in less than 2 hours and can also determine resistance to rifampin, one of the drugs used to treat TB. The information sheet describes how the Xpert MTB/RIF assay works, its advantages, how the results should be interpreted, what it means if RIF resistance is detected, not detected, or is indeterminate. Addresses for additional information are provided.

TB Silent Killer: FRONTLINE Documentary and Panel Discussion

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This webinar is a public forum and panel discussion convened to examine the global health challenges that TB presents, examine the limitations and challenges of current treatment options, and discuss the search for new and better TB drugs and other tools. A podcast, speakers' biographies, and a transcript is also available.

The Growing Threat of Multidrug-Resistant Gonorrhea

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This session of Grand Rounds explored the development of antibiotic resistance in gonorrhea as a growing public health concern because the United States gonorrhea control relies on effective antibiotic therapy. Topics discussed include Neisseria Gonorrhoeae Infections and antimicrobial treatment: Public health context and challenges; Molecular basis of resistance and importance of the laboratory in detection of resistance; Tools to combat multidrug resistance; and What public health can do now and in the future.

Building Capacity along the Continuum from Prevention to Care and Treatment for Key Populations in the Central America Region...

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Grant Amount: Approximate Total Fiscal Year Funding: $3,000,000. Within CDC Central America’s objective of strengthening sustainable key population services within a technical assistance framework, the purpose of this FOA is to support concrete efforts that assist Ministries of Health in Central America to lead manage, coordinate, and implement national responses to their respective concentrated epidemics while sustaining programmatic quality and coverage goals.

Surveys, Surveillance, and Informatics Involving HIV and TB in Botswana under the President's Emergency Plan for AIDS Relief ...

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Grant Amounts: Approximate Total Fiscal Year Funding: $2,950,000. Botswana has both a high prevalence of HIV (25% among persons 15-49 years of age) and a high incidence of TB (455 new cases per 100,000 population per year). Drug resistance is a concern with both diseases. High quality surveillance and monitoring data are needed for effective disease control efforts. This funding opportunity announcement (FOA) has two primary objectives. Both are meant to support ongoing efforts of the Botswana Ministry of Health (MOH).

MMWR: Approaches to Improving Adherence to Antituberculosis Therapy--South Carolina and New York, 1986-1991

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This report describes strategies used in South Carolina and New York City to improve adherence to antituberculosis (anti-TB) therapy and provides recommendations for improving patient adherence to anti-TB therapy. Patients with TB who fail to complete a standard course of anti-TB therapy are at increased risk for treatment failure and may play a role in both the emergence of drug-resistant strains of Mycobacterium TB and further spread of TB.

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