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Drug Abuse

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Funding Admin Form

PrEP for HIV Prevention among Substance Using Populations (R01 - Clinical Trial Optional)

NIDA is interested in research that addresses research gaps related to PrEP and its use among substance users, with the goals of improving PrEP management and implementation. Current US Public Health Service PrEP guidelines recommend PrEP for people who inject drugs (PWID) and mention alcohol and illicit drug use as potential concerns for clinical management. Only one clinical trial has evaluated PrEP among PWID and systematic data regarding the broader use of PrEP among substance users are limited.

Rural Communities Opioid Response Program – Neonatal Abstinence Syndrome (RCORP-NAS)

he Rural Communities Opioid Response Program (RCORP) is a Health Resources and Services Administration (HRSA) multi-year initiative aimed at reducing the morbidity and mortality of substance use disorder (SUD), including opioid use disorder (OUD), in high-risk, rural communities. This notice announces the opportunity to apply for funding under RCORP-Neonatal Abstinence Syndrome (RCORP-NAS).

Rural Health and Safety Education

The RHSE program proposals are expected to be community-based, outreach education programs, such as those conducted through Human Science extension outreach, that provides individuals and families with: Information as to the value of good health at any age; Information to increase individual or family’s motivation to take more responsibility for their own health; Information regarding rural environmental health issues that directly impact on human health; Informat

Avenir Award Program for Research on Substance Use Disorders and HIV/AIDS (DP2 Clinical Trial Optional)

Avenir means future in French, and the Avenir Award Program for Research on Substance Abuse and HIV/AIDS looks toward the future by supporting early stage investigators (ESI) proposing highly innovative studies that address NIH HIV/AIDS Research Priorities The Avenir Award Program for Research on Substance Abuse and HIV/AIDS will support creative individuals who wish to pursue innovative research at the nexus of substance abuse and HIV/AIDS. The nexus with drug abuse should be clearly described.

NIDA Avant-Garde Award Program for HIV/AIDS and Substance Use Disorder Research (DP1, Clinical Trial Optional)

The NIDA Avant-Garde Award Program for HIV/AIDS Research supports individual scientists of exceptional creativity who propose high-impact research that will open new areas of HIV/AIDS research relevant to drug abuse and/or lead to new avenues for prevention and treatment of HIV/AIDS among drug abusers. The term avant-garde is used to describe highly innovative approaches that have the potential to be transformative.

National Indian Health Outreach and Education

The purpose of this Indian Health Service (IHS) cooperative agreement is to further IHS’s mission and goals related to providing quality health care to the American Indian / Alaska Native community through outreach and education efforts with a focus on improving Indian health care, promoting awareness, visibility, advocacy, training, technical assistance, and education efforts. This program includes the following seven components, as described in this announcement: “Line Item 128 Health Education and Outreach funds;” “Health Care Policy Analysis and Review;” “Substance Abuse and S

Rural Communities Opioid Response Program - Planning

This notice announces the opportunity to apply for funding under the Rural Communities Opioid Response Program - Planning (RCORP-Planning). RCORP is a multi-year HRSA initiative with the goal of reducing morbidity and mortality resulting from substance use disorder (SUD), including opioid use disorder (OUD), in high risk rural communities. This funding opportunity, RCORP-Planning, will advance RCORP's overall goal by strengthening and expanding the capacity of rural communities to provide SUD/OUD prevention, treatment, and recovery services.

Exploring the Roles of Biomolecular Condensates (BMCs) in HIV replication, latency, or pathogenesis in the context of substance use disorders (R21/R33 Clinical Trial Not Allowed)

To support research projects exploring the roles of biomolecular condensates (BMCs) and their regulators in processes relevant to HIV/SIV infection, replication, latency, or pathogenesis in the context of substance use disorders. These processes could include studies exploring BMC involvement in HIV infection, HIV replication (including viral gene expression), HIV latency formation or maintenance (including chromatin structure), or HIV pathogenesis (including neurodegenerative processes).

Pilot and Feasibility Studies in Preparation for Drug and Alcohol Abuse Prevention Trials (R34 Clinical Trial Optional)

This Funding Opportunity Announcement (FOA) for R34 applications seeks to support: (a) pilot and/or feasibility testing of innovative new, revised, or adapted prevention intervention approaches to prevent or delay the initiation and onset of drug and alcohol use, the progression to misuse or problem use or alcohol and other substance use disorder, reduce drinking and driving and deaths related to impaired driving, prevent suicide attempts (nonfatal and fatal), and the drug- or alcohol-related acquisition or transmission of HIV infection and viral hepatitis among diverse populations and setting


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