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MMWR: Nucleic Acid Amplification Tests for Tuberculosis

This report summarizes potential uses of nucleic acid amplification (NAA) tests such as the Amplified Mycobacterium Tuberculosis Direct Test (MTD) for TB diagnosis and provides interim guidelines for the use of such tests. The report lists the current NAA tests, their FDA approved uses, their non-approved indications also known as off-label uses, limitations, and cautions.

MMWR: Characteristics of Foreign-Born Hispanic Patients with Tuberculosis - Eight US Counties Bordering Mexico, 1995

This report summarizes findings of the epidemiologic study conducted by health departments in the four US states bordering Mexico (Arizona, California, New Mexico, and Texas) to characterize patterns of immigration and migration among foreign-born Hispanic patients with TB and their behaviors in seeking health care. The 181 consenting Hispanic patients under treatment for TB during October 1, 1995 to January 5, 1996, completed a standardized questionnaire and additional data were obtained from medical charts and laboratory reports.

MMWR: Clinical Update: Impact of HIV Protease Inhibitors on the Treatment of HIV - Infected Tuberculosis Patients With Rifampin

This report describes approaches for managing patients with TB who are candidates for or who are undergoing protease inhibitor therapy and presents interim recommendations for managing these patients until additional data are available and formal guidelines are issued. Protease inhibitors interact with rifamycin derivatives, which are used to treat and prevent the mycobacterial infections commonly observed in patients with the HIV. The report provides background information on the management of TB and the three treatment options currently available for these patients.

MMWR: Exposure of Passengers and Flight Crew to Mycobacterium Tuberculosis on Commercial Aircraft, 1992-1995.

This report summarizes CDC and State health departments investigations and provides guidance about notification of passengers and flight crew after exposure to TB during travel on commercial aircrafts. From January 1993 through February 1995, CDC and State health departments completed an investigation of six instances in which passengers or flight crew traveled on commercial aircraft while infectious with TB.